Derick H. Lindquist
Departments of Psychology and Neuroscience
The Ohio State University
“Impaired synaptic plasticity and cognitive function in a rat model of fetal alcohol spectrum disorder”
Fetal alcohol spectrum disorders (FASD) refer to a range of physical and mental impairments that can occur in the offspring of women who consume alcohol during pregnancy. Our lab utilizes a rat model of FASD in order to investigate the neurotoxic effects of ethanol on forebrain development and cognitive function. This talk will synthesize observed behavioral deficits in Pavlovian conditioning with ethanol-induced disruptions in hippocampal NMDA receptor subunit composition and synaptic plasticity.