Dr. Oleg Paliy, Ph.D.

Assistant Professor

260 Diggs, Department of Biochemistry and Molecular Biology, 3640 Col. Glenn Hwy, Dayton, OH 45435

e-mail:

Education:

B.Sc.+M.Sc.: Lviv State University, Lviv, Ukraine. 1992-1997. Genetics and Genetic Engineering.

Ph.D.: University of Manchester, Manchester, UK. 1997-2001. Microbiology, Molecular and Structural Biology.

Postdoctoral: University of California at Berkeley, Berkeley, CA, USA. 2001-2004. Microbiology and Systems Biology.

• Role of intestinal bacteria in human health and in gastrointestinal diseases such as IBD and IBS

• Host-pathogen interactions and stress tolerance of pathogenic Escherichia coli

• Use of genetic engineering and mathematical modeling to study principles of gene and genome functions

• Standard microbiology techniques

• Standard cloning methods

• Gene expression profiling with microarrays

• Microbial community analysis by 16S RNA sequencing and phylogenetic microarrays

• Bioinformatics and computational biology

• Biostatistics and phylogenetic analysis
  

• Research highlighted:

  Collaboration on microbiota studies between our and Dr. S. Michail labs is highlighted in the June issue of Boonshoft School of Medicine Vital Signs magazine (pdf).

• Student award:

  Jacqueline Link, an undergraduate student in the lab, has received an Undergraduate Research Support Grant award from WSU for 2009/10 academic year. Jackie is helping on the mercury biosensor project.

• Paper published:

  O. Paliy, H. Kenche, F. Abernathy, and S. Michail. High-throughput quantitative analysis of the human intestinal microbiota with a phylogenetic microarray (2009) Appl. Environ. Microbiol. 75(11), 3572-9. [Impact Factor: 4.00 (2007 ISI)]

• Students present posters:

  R. Agans, L. Rigsbee, H. Kenche, F. Abernathy, S. Michail, and O. Paliy. Pilot high-throughput analyses of fecal intestinal microbiota with custom phylogenetic microarray. OBASM 2009 and OCCBIO 2009

  B. Withman, T. Gunasekera, and O. Paliy. Transcriptional responses of uropathogenic E. coli to osmotic pressure caused by salt or urea. OBASM 2009 and OCCBIO 2009

• Paper published:

  T.S. Gunasekera, L.N. Csonka, and O. Paliy. Genome-wide transcriptional responses of Escherichia coli K12 to heat and osmotic stresses (2008) J. Bacteriology 190 (10), 3712-20. [Impact Factor: 4.01 (2007 ISI)]

• NIH NCCAM [2008-2010] "Using Affymetrix Microflora array to study microflora composition in children with IBS"

• WSU SoM Research Challenge [2007-2008] "Design and implementation of custom GeneChip community microarray to study human microflora"

• WSU Seed Grant [2006] "E. coli response to high temperature and increased osmolarity at gene expression level"

• WBI Center grant [2004-2006] "Center of excellence in cellular dynamics and engineering"