B number Weber - down-regulated genes Weber - up-regulated genes Gene Description C2/C1 C5/C4 b4016 aceK isocitrate dehydrogenase kinase/phosphatase 0.3 0.3 b4017 arpA regulator of acetyl CoA synthetase -0.9 0.3 b3570 bax putative ATP-binding protein 1.5 3.2 b0484 copA Cu(I)-translocating P-type ATPase 0.7 -0.2 b2417 crr PTS system, glucose-specific IIA component 0.2 -0.1 b0339 cynT carbonic anhydrase -1.0 -0.1 b3639 dfp flavoprotein affecting synthesis of DNA and pantothenate metabolism 0.0 0.1 b2321 div/flk flagellar assembly protein 0.0 0.2 b0812 dps global regulator, starvation conditions 0.6 -0.4 b0912 himD integration host factor (IHF), beta subunit; site-specific recombination 0.1 -0.5 b0072 leuC 3-isopropylmalate isomerase (dehydratase) subunit 0.2 0.0 b0181 lpxA UDP-N-acetylglucosamine acetyltransferase; lipid A biosynthesis 0.5 1.1 b3008 metC cystathionine beta-lyase (beta-cystathionase) 0.3 0.3 b3941 metF 5,10-methylenetetrahydrofolate reductase -0.1 0.3 b0783 moaC molybdopterin biosynthesis, protein C 0.4 -0.3 b0827 moeA molybdopterin biosynthesis 0.2 0.2 b1482 osmC osmotically inducible protein 1.4 0.9 b4376 osmY hyperosmotically inducible periplasmic protein 1.1 0.1 b1896 otsA trehalose-6-phosphate synthase 1.4 0.6 b1897 otsB trehalose-6-phosphate phophatase, biosynthetic 0.9 1.3 b4111 proP low-affinity transport system; proline permease II 0.8 1.6 b2677 proV ATP-binding component of transport system for glycine, betaine and proline 4.1 6.2 b2678 proW high-affinity transport system for glycine betaine and proline 4.3 5.7 b2679 proX high-affinity transport system for glycine betaine and proline 3.8 5.1 b0415 ribE riboflavin synthase, beta chain 0.0 -0.2 b1652 rnt RNase T, degrades tRNA 0.4 0.8 b2741 rpoS RNA polymerase, sigma S (sigma38) factor; synthesis of many growth phase related proteins 0.2 0.7 b2011 sbcB exonuclease I, 3' --> 5' specific; deoxyribophosphodiesterase 0.2 0.3 b1098 tmk thymidylate kinase 0.0 0.1 b2894 xerD site-specific recombinase 0.0 0.4 b0413 ybaD orf, hypothetical protein 0.1 -0.1 b0539 ybcC putative exonuclease (EC 3.1.11.3) similar to lambda -1.2 -2.5 b0601 ybdM orf, hypothetical protein -0.5 0.3 b0607 ybdQ orf, hypothetical protein -0.9 -0.2 b0753 ybgS putative homeobox protein 0.0 0.3 b1253 yciA orf, hypothetical protein -0.1 0.2 b2101 yegW putative transcriptional regulator -0.2 0.0 b2524 yfhJ orf, hypothetical protein 0.2 -0.4 b4048 yjbM orf, hypothetical protein -1.2 0.1 b4248 yjgH orf, hypothetical protein -0.7 -0.1 b1155 ymfS orf, hypothetical protein -1.4 0.2 b0605 ahpC alkyl hydroperoxide reductase, C22 subunit; detoxification of hydroperoxides 0.5 -0.6 b1415 aldA aldehyde dehydrogenase, NAD-linked 0.9 2.3 b4085 alsE putative epimerase -0.8 0.5 b0978 appC probable third cytochrome oxidase, subunit I -0.9 -4.2 b1693 aroD 3-dehydroquinate dehydratase 0.0 -0.8 b3433 asd aspartate-semialdehyde dehydrogenase 0.3 0.0 b3731 atpC membrane-bound ATP synthase, F1 sector, epsilon-subunit -0.2 0.0 b3736 atpF membrane-bound ATP synthase, F0 sector, subunit b 0.2 -0.2 b3735 atpH membrane-bound ATP synthase, F1 sector, delta-subunit 0.2 0.0 b3739 atpI membrane-bound ATP synthase, dispensable protein, affects expression of atpB 0.0 0.4 b0032 carA carbamoyl-phosphate synthetase, glutamine (small) subunit -0.2 0.6 b0033 carB carbamoyl-phosphate synthase large subunit -0.4 0.7 b3556 cspA cold shock protein 7.4, transcriptional activator of hns 0.0 0.2 b0430 cyoC cytochrome o ubiquinol oxidase subunit III 0.2 0.0 b2752 cysD ATP:sulfurylase (ATP:sulfate adenylyltransferase), subunit 2 -0.7 -1.0 b2762 cysH 3'-phosphoadenosine 5'-phosphosulfate reductase 0.1 -1.0 b2763 cysI sulfite reductase, alpha subunit -0.2 -0.9 b2764 cysJ sulfite reductase (NADPH), flavoprotein beta subunit -0.2 -1.0 b2414 cysK cysteine synthase A, O-acetylserine sulfhydrolase A 0.0 -0.6 b2421 cysM cysteine synthase B, O-acetylserine sulfhydrolase B -0.6 -0.5 b2423 cysW sulfate transport system permease W protein -0.3 -0.5 b0031 dapB dihydrodipicolinate reductase 0.3 0.5 b3892 fdoI formate dehydrogenase, cytochrome B556 (FDO) subunit 0.1 0.0 b1334 fnr transcriptional regulation of aerobic, anaerobic respiration, osmotic balance 0.3 0.5 b2153 folE GTP cyclohydrolase I 0.2 -0.3 b2169 fruB PTS system, fructose-specific IIA/fpr component -0.7 0.8 b0890 ftsK cell division protein 0.8 0.5 b3933 ftsN essential cell division protein -0.1 0.1 b0095 ftsZ cell division; forms circumferential ring; tubulin-like GTP-binding protein and GTPase 0.1 -0.3 b1779 gapA glyceraldehyde-3-phosphate dehydrogenase A 0.1 -0.3 b2096 gatY tagatose-bisphosphate aldolase 1 -0.7 0.5 b2903 gcvP glycine decarboxylase, P protein of glycine cleavage system 0.2 -0.4 b1761 gdhA NADP-specific glutamate dehydrogenase 0.1 0.4 b3429 glgA glycogen synthase 0.2 -0.1 b3212 gltB glutamate synthase, large subunit 0.7 -0.2 b3213 gltD glutamate synthase, small subunit 0.6 -0.1 b0755 gpmA phosphoglyceromutase 1 0.3 -0.4 b2021 hisC histidinol-phosphate aminotransferase 0.1 -0.7 b4000 hupA DNA-binding protein HU-alpha (HU-2) 0.4 -0.3 b0440 hupB DNA-binding protein HU-beta, NS1 (HU-1) 0.0 0.0 b0977 hyaF nickel incorporation into hydrogenase-1 proteins -0.8 -1.5 b0026 ileS isoleucine tRNA synthetase 0.5 0.3 b0918 kdsB CTP:CMP-3-deoxy-D-manno-octulosonate transferase 0.0 -0.1 b0071 leuD isopropylmalate isomerase subunit 0.4 0.0 b1677 lpp murein lipoprotein 0.0 -0.7 b3829 metE tetrahydropteroyltriglutamate methyltransferase 1.1 0.8 b3396 mrcA peptidoglycan synthetase; penicillin-binding protein 1A -0.3 0.8 b0635 mrdA cell elongation, e phase; peptidoglycan synthetase; penicillin-binding protein 2 0.1 0.6 b3189 murA first step in murein biosynthesis;UDP-N-glucosamine 1-carboxyvinyltransferase 0.0 0.0 b0569 nfrB bacteriophage N4 receptor, subunit, inner membrane protein -0.9 0.1 b2284 nuoF NADH dehydrogenase I chain F 1.2 -0.2 b0929 ompF outer membrane protein 1a (Ia;b;F) -0.3 -0.6 b0565 ompT outer membrane protein 3b (a), protease VII 0.3 -0.3 b3724 phoU negative regulator for pho regulon and putative enzyme in phosphate metabolism -0.4 -0.9 b2891 prfB peptide chain release factor RF-2 0.2 -0.1 b4201 priB primosomal replication protein N 0.2 0.4 b3300 prlA putative ATPase subunit of translocase 0.2 0.1 b0243 proA gamma-glutamylphosphate reductase 0.0 -0.6 b1305 pspB phage shock protein -0.1 0.4 b3204 ptsN phosphotransferase system enzyme IIA, regulates N metabolism 0.5 -0.2 b2312 purF amidophosphoribosyltransferase = PRPP amidotransferase 0.1 -0.3 b4245 pyrB aspartate carbamoyltransferase, catalytic subunit -0.7 2.2 b3751 rbsB D-ribose periplasmic binding protein 0.3 0.4 b1564 relB negative regulator of translation -0.2 -0.1 b3320 rplC 50S ribosomal subunit protein L3 0.4 -0.2 b3319 rplD 50S ribosomal subunit protein L4, regulates expression of S10 operon 0.2 0.1 b3308 rplE 50S ribosomal subunit protein L5 0.2 -0.3 b3305 rplF 50S ribosomal subunit protein L6 0.2 0.0 b4203 rplI 50S ribosomal subunit protein L9 0.1 0.5 b3186 rplU 50S ribosomal subunit protein L21 0.3 -0.1 b3318 rplW 50S ribosomal subunit protein L23 0.4 0.0 b3309 rplX 50S ribosomal subunit protein L24 0.3 -0.1 b1717 rpmI 50S ribosomal subunit protein A -0.2 -0.3 b0911 rpsA 30S ribosomal subunit protein S1 0.3 -0.1 b3230 rpsI 30S ribosomal subunit protein S9 -0.2 0.5 b3321 rpsJ 30S ribosomal subunit protein S10 0.4 -0.2 b3307 rpsN 30S ribosomal subunit protein S14 0.2 -0.2 b4202 rpsR 30S ribosomal subunit protein S18 0.2 0.3 b3316 rpsS 30S ribosomal subunit protein S19 0.2 0.0 b0023 rpsT 30S ribosomal subunit protein S20 -0.1 0.2 b0721 sdhC succinate dehydrogenase, cytochrome b556 0.7 0.6 b0722 sdhD succinate dehydrogenase, hydrophobic subunit 0.3 0.1 b3349 slyD FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) 0.1 -0.2 b0729 sucD succinyl-CoA synthetase, alpha subunit 0.4 0.1 b3017 sufI suppressor of ftsI -0.2 0.0 b0004 thrC threonine synthase 0.0 0.5 b1719 thrS threonine tRNA synthetase 0.2 0.0 b0436 tig trigger factor; a molecular chaperone involved in cell division 0.4 0.0 b1274 topA DNA topoisomerase type I, omega protein 0.2 0.3 b1324 tpx thiol peroxidase 0.2 -0.1 b2607 trmD tRNA methyltransferase; tRNA (guanine-7-)-methyltransferase 0.1 -0.1 b1261 trpB tryptophan synthase, beta protein 0.0 0.2 b3495 uspA universal stress protein; broad regulatory function? -0.1 -0.2 b0682 ybfN orf, hypothetical protein -1.0 -0.2 b0944 ycbF putative chaperone -0.2 0.7 b0983 yccZ putative function in exopolysaccharide production -0.5 0.0 b1016 ycdN_1 orf, hypothetical protein -0.2 0.9 b1191 ycgO orf, hypothetical protein -0.1 0.9 b1701 ydiD putative ligase/synthetase -0.5 0.4 b3233 yhcB orf, hypothetical protein 0.1 -0.2 b3584 yiaT putative outer membrane protein -0.8 0.1 b2140 yohI putative regulator protein 0.0 0.5