B number Gene Name Gene Description C4/C1 - Fold Change C5/C2 - Fold Change Richmond - down-regulated genes Richmond - up-regulated genes b3686 ibpB heat shock protein 1.5 3.2 327.2 b3687 ibpA heat shock protein 2.3 2.1 297.4 b0015 dnaJ chaperone with DnaK; heat shock protein 1.5 1.6 85.3 b4142 groS GroES, 10 Kd chaperone binds to Hsp60 in pres. Mg-ATP, suppressing its ATPase activity 2.3 1.6 77.5 b0014 dnaK chaperone Hsp70; DNA biosynthesis; autoregulated heat shock proteins 2.0 1.5 58.5 b3400 hslR Hsp15. DNA/RNA binding heat shock protein 1.3 1.3 51.3 b4140 fxsA Suppressor of F exclusion of bacteriophage T7. -1.1 1.4 50.7 b4143 groL GroEL, chaperone Hsp60, peptide-dependent ATPase, heat shock protein 2.5 1.7 37.9 b2592 clpB heat shock protein 2.7 2.6 36.5 b1829 htpX heat shock protein, integral membrane protein 1.9 1.1 36.1 b0400 phoR positive and negative sensor protein for pho regulon -3.1 -1.4 34.5 b0966 yccV orf, hypothetical protein 1.3 1.6 34.3 b0473 htpG chaperone Hsp90, heat shock protein C 62.5 2.4 2.0 33.8 b0016 yi81_1 IS186 hypothetical protein 1.3 1.3 32.9 b1967 yedU orf, hypothetical protein 18.5 12.8 30.5 b2394 yi81_3 IS186 hypothetical protein 1.0 1.0 29.6 b0315 yahA orf, hypothetical protein 1.3 6.6 28.9 b0399 phoB positive response regulator for pho regulon, sensor is PhoR (or CreC) -4.0 -1.9 28.2 b0582 yi81_2 IS186 hypothetical protein 1.0 1.0 27.3 b1060 yceP orf, hypothetical protein -2.3 -1.4 25.5 b2614 grpE phage lambda replication; host DNA synthesis; heat shock protein; protein repair 1.9 1.5 24.1 b0017 yi82_1 IS186 and IS421 hypothetical protein -3.8 1.4 22.8 b3343 yheL orf, hypothetical protein 1.1 -1.1 22 b3401 hslO Hsp33. Redox regulated chaperone 1.1 1.3 21.6 b0439 lon DNA-binding, ATP-dependent protease La; heat shock K-protein 1.3 1.0 20.3 b1322 ycjF orf, hypothetical protein 1.6 2.1 19.8 b3498 prlC oligopeptidase A 1.1 1.1 16.7 b3932 hslV heat shock protein hslVU, proteasome-related peptidase subunit 1.5 1.4 16.2 b4209 ytfE orf, hypothetical protein 1.0 1.4 13.7 b0210 yafE putative biotin synthesis protein -1.9 -1.5 12.2 b1112 ycfR orf, hypothetical protein 2.6 1.5 12.2 b3635 mutM formamidopyrimidine DNA glycosylase -1.0 1.2 12.2 b3399 yrfG putative phosphatase 1.0 -1.1 12.1 b4171 miaA delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase 1.3 1.3 11.9 b3931 hslU heat shock protein hslVU, ATPase subunit, homologous to chaperones 1.8 1.5 10.3 b0492 ybbN putative thioredoxin-like protein 1.4 1.0 9.9 b0660 ybeZ putative ATP-binding protein in pho regulon 1.4 1.2 9.6 b3293 yhdN orf, hypothetical protein 1.7 1.3 9.5 b3179 rrmJ cell division protein -1.1 -1.4 9.1 b2613 yfjD putative transport protein -1.1 -1.1 9 b1530 marR multiple antibiotic resistance protein; repressor of mar operon 1.4 1.9 8.5 b3067 rpoD RNA polymerase, sigma(70) factor; regulation of proteins induced at high temperatures 1.9 1.3 7.7 b0209 yafD orf, hypothetical protein -1.1 -1.1 6.7 b3022 ygiU orf, hypothetical protein 1.0 2.5 6.7 b0881 yljA orf, hypothetical protein 1.3 1.4 6.5 b1531 marA multiple antibiotic resistance; transcriptional activator of defense systems 3.3 4.1 6.2 b1274 topA DNA topoisomerase type I, omega protein -1.1 -1.0 5.9 b0659 ybeY orf, hypothetical protein 1.6 1.2 5.8 b4239 treC trehalase 6-P hydrolase -1.0 5.4 5.8 b0880 cspD stress induced DNA replication inhibitor. 2.0 3.1 5.5 b0879 macB putative ATP-binding component of a transport system 1.0 1.0 5.2 b4141 yjeH putative transport -1.9 -1.1 5.1 b4172 hfq host factor I for bacteriophage Q beta replication, a growth-related protein -1.2 -1.3 4.5 b4131 cadA lysine decarboxylase 1 -1.7 1.3 4.4 b0316 yahB putative transcriptional regulator LYSR-type -2.6 -1.4 4.3 b2193 narP nitrate/nitrite response regulator (sensor NarQ) 1.6 1.9 4.2 b3685 yidE putative transport protein -2.1 -1.2 3.9 b4246 pyrL pyrBI operon leader peptide -1.8 1.4 3.9 b0882 clpA ATP-binding component of serine protease 1.1 -1.3 3.8 b4398 creB catabolic regulation response regulator -1.4 1.5 3.4 b0437 clpP ATP-dependent proteolytic subunit of clpA-clpP serine protease, heat shock protein F21.5 1.1 -1.0 3.3 b4173 hflX GTP - binding subunit of protease specific for phage lambda cII repressor -1.0 -1.1 3.3 b0033 carB carbamoyl-phosphate synthase large subunit 1.4 3.0 3.2 b1874 cutC copper homeostasis protein -1.1 1.2 3.2 b4245 pyrB aspartate carbamoyltransferase, catalytic subunit -2.1 3.8 3.1 b0438 clpX ATP-dependent specificity component of clpP serine protease, chaperone 1.0 -1.2 2.9 b4117 adiA biodegradative arginine decarboxylase -1.5 1.7 2.9 b0281 intF putative phage integrase 4.1 4.9 2.8 b0032 carA carbamoyl-phosphate synthetase, glutamine (small) subunit 1.2 2.3 2.7 b0374 yaiU putative flagellin structural protein -3.1 1.1 2.7 b4115 yjdE putative amino acid/amine transport protein, cryptic 1.0 1.0 2.5 b3402 yhgE putative transport -1.5 1.0 2.4 b2476 purC phosphoribosylaminoimidazole-succinocarboxamide synthetase = SAICAR synthetase 1.5 1.2 2.2 b2497 uraA uracil transport -3.6 1.2 2.2 b2796 sdaC probable serine transporter 1.3 1.5 2.2 b0336 codB cytosine permease/transport -2.7 1.4 2.1 b0491 ybbM putative metal resistance protein -1.6 -1.4 2 b0522 purK phosphoribosylaminoimidazole carboxylase = AIR carboxylase, CO(2)-fixing subunit -1.1 1.1 2 b4132 cadB transport of lysine/cadaverine -2.5 1.6 2 b0523 purE phosphoribosylaminoimidazole carboxylase = AIR carboxylase, catalytic subunit 1.0 1.1 1.9 b3413 yhgH orf, hypothetical protein -1.2 -1.4 1.9 b2313 cvpA membrane protein required for colicin V production 1.7 1.2 1.8 b2500 purN phosphoribosylglycinamide formyltransferase 1 1.0 -1.2 1.5 b0572 cusC putative resistance protein -1.2 -1.9 1.4 b3280 yrdB orf, hypothetical protein -1.1 -1.7 1.3 b3512 yhiE orf, hypothetical protein 9.5 3.7 1.3 b4244 pyrI aspartate carbamoyltransferase, regulatory subunit -2.3 3.8 1.3 b3114 tdcE probable formate acetyltransferase 3 -1.7 1.7 1.2 b0973 hyaB hydrogenase-1 large subunit 5.3 1.5 1 b2572 rseA sigma-E factor, negative regulatory protein 1.5 1.3 1 b2573 rpoE RNA polymerase, sigma-E factor; heat shock and oxidative stress 1.7 1.7 1 b3816 corA Mg2+ transport, system I 1.0 1.6 1 b4208 cycA transport of D-alanine, D-serine, and glycine -2.3 -1.5 1 b0337 codA cytosine deaminase -1.6 1.3 -1 b1062 pyrC dihydro-orotase 1.3 1.3 -1 b1903 b1903 orf, hypothetical protein -1.6 1.6 -1 b2498 upp uracil phosphoribosyltransferase -2.3 1.0 -1 b3669 uhpA response regulator, positive activator of uhpT transcription (sensor, uhpB) -1.4 1.6 -1 b0116 lpdA lipoamide dehydrogenase (NADH); component of 2-oxodehydrogenase and pyruvate complexes; L-protein of glycine cleavage complex 1.2 1.3 -1.1 b0945 pyrD dihydro-orotate dehydrogenase -1.3 2.1 -1.1 b1132 ycfC orf, hypothetical protein -1.0 1.0 -1.2 b2945 endA DNA-specific endonuclease I -1.9 1.4 -1.2 b1593 ynfK orf, hypothetical protein 1.0 1.2 -1.4 b2508 guaB IMP dehydrogenase 1.4 1.1 -1.8 b0411 tsx nucleoside channel; receptor of phage T6 and colicin K -2.2 1.2 -2.2 b1131 purB adenylosuccinate lyase 2.0 1.3 -2.3 b1782 mipA Scaffolding protein for murein-synthesising holoenzyme. -1.2 1.1 -2.8 b1888 cheA sensory transducer kinase between chemo- signal receptors and CheB and CheY -9.7 -9.9 -3.3 b2507 guaA GMP synthetase (glutamine-hydrolyzing) 1.0 1.0 -3.3 b1924 fliD flagellar biosynthesis; filament capping protein; enables filament assembly -29.7 -22.6 -4.8 b1887 cheW positive regulator of CheA protein activity -9.8 -11.1 -6 b2297 pta phosphotransacetylase 1.3 1.8 -6 b2779 eno enolase 2.0 1.5 -6.7 b2551 glyA serine hydroxymethyltransferase -1.0 -1.0 -8.1 b1676 pykF pyruvate kinase I (formerly F), fructose stimulated 2.3 1.4 -9.2 b0903 pflB formate acetyltransferase 1 1.0 1.0 -10 b2286 nuoC NADH dehydrogenase I chain C, D 2.2 1.2 -10.4 b2925 fbaA fructose-bisphosphate aldolase, class II 1.4 1.1 -12.5 b1076 flgE flagellar biosynthesis, hook protein -27.4 -25.5 -22.7