James E. Olson, Ph.D.
Cornell University - 1972 - B.S. Engineering Physics
University of California, Berkeley - 1978 - Ph.D. Biophysics
email: james.olson@wright.edu
|
James E. Olson, Ph.D. Cornell University - 1972 - B.S. Engineering Physics University of California, Berkeley - 1978 - Ph.D. Biophysics email: james.olson@wright.edu |
Mechanisms of brain adaptation to edema,
Cellular volume regulation,
Membrane channel activation during apoptosis, Blood-brain barrier water
transport
Professor of Emergency Medicine , Wright State University School of Medicine
Professor of Neuroscience, Cell Biology, and Physiology , Wright State University School of Medicine
Graduate Faculty Member of Biomedical Sciences Program
Articles on our research and teaching:
Society for Neuroscience 2010 Science Educator Award
Wright State University's Vital Signs
magazine. (Click here for the
entire issue)
Article in Dayton
Medicine.
Kettering Medical Center's Neuroscience Directions.
(Click here for the entire issue)
Society for Neuroscience Quarterly Newsletter (See article on bottom of page - Click here for the entire issue)
American College of Emergency Medicine - ACEP News.
A two-minute summary of one of our research projects, "The Talking RVD Blues", was
performed at the
2006 Wright State University Central Research Forum as part of the Data
Blitz.
(Video courtesy of Melissa Bautista)
Then we took it on the road to San Diego. Hear "The Talking RVD Blues"
performed at the
Society for Neuroscience Music Social in 2007.
(Video courtesy of Dominic D'Agostino)
Lab Photo, July 2011
Standing left to right: Robert Spokane (Visiting Scientist), Megan Woods
(Graduate-Prep Student), Nancy Andrews (Research Secretary), Sergei Robinson
(Masters Student), Guang-ze Li (Research Associate), Amanda Freeman (M.D./Ph.D.
Student), Jim Olson (Research Laboratory Director), Michelle
Durrant (Undergraduate Summer Research Fellow), Mandy Gutwein (Masters Student),
Brian Tucker (Masters Student), Courtney Moore (Masters
Student).
Sitting in front: The Leasure Family: Cressie, Kevin, Acacia, and James
Ohio Research Incentive Fund, Non-invasive Assessment of Brain Edema using Electromagnetic Interrogation and Sensing. Co-investigator with Ronald Riechers
Wallace Kettering Neuroscience Institute, Development of nanoparticle MRI contrast agents. Co-Investigators: Robert Spokane and Michael Kent
National Institutes of Health, Balance of Angiotensin II/Angiotensin(1-7):
A target in Ischemic Stroke. Co-Investigator with Yanfang Chen (PI)
Chen, Shuzhen; Li, Guangze; Zhang, Wenfeng; Wang, Jinju; Sigmund, Curt D.; Olson, James E.; and Chen Yanfang. Ischemia induced brain damage is enhanced in human renin and angiotensin double transgenic mice. American Journal of Physiology, 297(5):R1526-R1531, 2009.
D'Agostino, Dominic P.; Olson, James E.; and Dean, Jay B. Acute hyperoxia increases lipid peroxidation and induces plasma membrane blebbing in human U87 glioblastoma cells. Neuroscience,159:1011-1022, 2009.
Li, Guangze and Olson, James E. Purinergic activation of anion conductance and osmolyte efflux in cultured rat hippocampal neurons. American Journal of Physiology (Cell Physiology), 295(6):C1550-C1560, 2008.
Stepaniak, Phillip C.; Hamilton, Glenn C.; Olson, James E.; Gilmore, Stevan
M.; Stizza, Denis M.; and Beck, Bradley. Physiologic effects of simulated
+Gx orbital reentry in primate models of hemorrhagic shock. Aviation, Space, and Environmental Medicine,
78(4 Suppl.):A14-A25, 2007.
Olson,
James E. and Eduardo Martinho Jr. Regulation of
taurine transport in rat hippocampal neurons by hypoosmotic
swelling. Journal of
Neurochemistry, 96:1375-1389, 2006.
Olson, James E. and
Kreisman, Norman R. Volume regulation in the hippocampus.
In: Cell Volume Regulation
and Cellular Signaling. P. Lauf and N. Adragna (eds.) New
York: Kluwer Plenum, pp. 331-338, 2005.
Li, Guangze and Olson, James E. Cell volume modifies an ATP-sensitive anion conductance in cultured hippocampal astrocytes. In: Cell Volume Regulation and Cellular Signaling. P. Lauf and N. Adragna (eds.) New York: Kluwer Plenum, pp. 405-406, 2005.
Muehlberger, Patrick M.; Pilmanis, Andrew A.; Webb, James T.; and Olson,
James E. Altitude decompression sickness symptom
resolution during descent to ground level. Aviation, Space, and Environmental Medicine,
75(6):496-499, 2004.
Olson, James E.; Li,
Guangze; Wang, Ling; and Lu, Luo. Volume regulated anion
conductance in cultured rat cerebral astrocytes requires calmodulin
activity. Glia,
46(4):391-401, 2004.
Li, Guangze and Olson, James E.
Extracellular ATP activates
chloride
and taurine conductanes in cultured hippocampal neurons. Neurochemical
Research, 29(1):239-246, 2004.
Olson, James E.; Kreisman, Norman R.; Lim, Jenny; Hoffman, Beth; Schelble, Dana; and Leasure, James. Taurine and cellular volume regulation in the hippocampus, In: Taurine 5. B. Lombardini, S. Schaffer; and J. Azuma (eds.) New York: Kluwer Plenum, pp. 107-114, 2003.
Li, Guang-ze; Liu, Yin; and Olson, James E. Calcium/calmodulin-modulated chloride and taurine conductances in cultured rat astrocytes, Brain Research, 925, 1-8, 2002.
Xu, Dashong; Wang, Ling; Olson, James E.; and Lu, Luo. Asymmetrical response of p38 kinase activation to volume changes in primary rat astrocytes, Experimental Biology and Medicine, 226, 927-933, 2001.
Mulkey, Daniel K; Henderson, Richard A. III; Olson, James E.; Putnam, W. Robert; and Dean, B. Jay. Oxygen measurements in brainstem slices exposed to normobaric hyperoxia and hyperbaric oxygen. Journal of Applied Physiology, 90, 1887-1899, 2001.
Chellis, Mary; Olson, James E.; Augustine, James; and Hamilton, Glenn C. Evaluation of missed diagnoses for patients admitted from the emergency department. Academic Emergency Medicine, 8, 125-130, 2001.
Published Artistic and Reflective Collaborations:
Olson, James E. and Singer, Jonathan. Bridge over the river cry. Academic Emergency Medicine, 17(6):648, 2010.
Olson, James E. and Singer, Jonathan. Anagram for "Neurologic Exam: Grossly Normal". Academic Emergency Medicine, 17(5):572, 2010.
Olson, James E. and Singer, Jonathan. A tribute to permanent night people. Academic Emergency Medicine, 17(5):574, 2010.
Olson, James E. and Singer, Jonathan. Was the forensic oratory of a global event truthful sorrow? Academic Emergency Medicine, 17(4):467, 2010.
Olson, James E. and Singer, Jonathan. Can we prosper in the barren landscape? Academic Emergency Medicine, 17(3):347, 2010.
Olson, James E. and Singer, Jonathan. Now in the womb of mother Earth. Academic Emergency Medicine, 17(2):230, 2010.
Olson, James E. and Singer, Jonathan. Justifiable piracy in our academic waters. Academic Emergency Medicine, 16(12):1390, 2009.
Olson, James E. and Singer, Jonathan. DPCT: Adding to the cardiac predictive terminology. Academic Emergency Medicine, 16(10):1036, 2009.
Olson, James E. and Singer, Jonathan. SIRS is not a playful act. Academic Emergency Medicine, 16(8):813, 2009.
Olson, James E. and Singer, Jonathan. While getting to the other side. Academic Emergency Medicine, 16(8):710, 2009.
Olson, James E. and Singer, Jonathan. The Match. Academic Emergency Medicine, 16(7):689, 2009.
Olson, James E. and Singer, Jonathan. Longevity
had its place and I'm concerned about that now. Academic
Emergency Medicine, 16(1):49, 2009.
Olson, James E.
and Singer, Jonathan. Thoughts from my visit to Salvatore Vicario.
Academic Emergency Medicine, 15(7):648,
2008.
Olson, James E.
and Singer, Jonathan. At the time of my need, father returns the favor.
Academic Emergency Medicine, 15(1):31,
2008.
Olson, James E.
and Singer, Jonathan. Can I ever be forgiven? Academic Emergency Medicine, 14(12):1198-1199,
2007.
Olson, James E. and Singer, Jonathan. Please excuse Jonny, he has prostate cancer. Academic Emergency Medicine, 14(10):912-913, 2007.
Olson, James E.
and Singer, Jonathan. The collective inefficiencies of cubicles and
curtains. Academic Emergency Medicine,
14 (7):615, 2007.
Olson, James E. and Singer, Jonathan. Predicting certainty in spite of evidence to the contrary. Academic Emergency Medicine, 14(2):162, 2007.
Olson,
James E. and Singer, Jonathan. At the discharge
counter. Academic Emergency
Medicine, 14(1):73, 2007.
Olson, James E.
and Singer, Jonathan. Diagnostic crayoning while awaiting our
ED's healing art. Academic Emergency
Medicine, 13(12)1354, 2006.
Olson,
James E. and Singer, Jonathan. Justice before your
peers. Academic Emergency
Medicine, 13(10):1019, 2006.
Olson,
James E. and Singer,
Jonathan. Scientific assemblies ordain convention. Annals of Emergency Medicine,
48(3):337, 2006.
Olson,
James E. and Singer, Jonathan. Servicing the petite summer
menu. Academic Emergency
Medicine, 13(9):930, 2006.
Olson, James E. and Singer, Jonathan. Scholastic sharecropping. Academic Emergency Medicine, 13(3):263, 2006.
Olson, James E. and Singer, Jonathan. How fertile is an RRC-EM visit? Academic Emergency Medicine, 12(7):628, 2005.
Olson, James E. and Singer, Jonathan. Do not be stranded by signals not perfectly understood. Annals of Emergency Medicine, 45(5):559, 2005.
Olson, James E. and Singer, Jonathan. A shift where the keel plowed air. Academic Emergency Medicine, 12(3):196, 2005
Olson, James E. and Singer, Jonathan. Of shoes and codes and sealing bags. Academic Emergency Medicine, 11(12):1372, 2004.
Olson,
James E. and Singer, Jonathan. The artistry of
attending in the ED. Academic
Emergency Medicine, 11(10):1066, 2004.
Olson,
James E. and Singer, Jonathan. One ancient's path
to the graveyard. Academic
Emergency Medicine, 11(10):1013, 2004.
Olson,
James E. and Singer, Jonathan. Admonishment for
the expert witness. Academic
Emergency Medicine, 11(5):618, 2004.
Olson,
James E. and Singer, Jonathan. Keeping a precious
moment between the pages. Academic
Emergency Medicine, 11(5):434, 2004.
Olson, James E. and Singer, Jonathan. Oh drunken doctor, what did ya' do? Acdemic Emergency Medicine, 11(5):432, 2004.
Olson,
James E. and Singer, Jonathan. Field of study
for the retired chair. Academic
Emergency Medicine, 11(3):306, 2004.
Olson,
James E. and Singer, Jonathan. Can we free our
professors? Academic Emergency
Medicine, 11(2):161, 2004.