Wright State University home page. From Invention to Market 2004: Celebrating the 
Commercial Power of Innovation

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For further information contact:
Isabelle Gorrillot, D.Sc.
Assoc. Dir. for Technology Transfer
Research & Sponsored Programs
(937) 775-2651
Fax (937) 775-3781



Diagnostic Test for Sjogren Syndrome
Thomas L. Brown, Ph.D. (WSU), & Jon Morrow, M.D., Ph.D. (Yale University School of Medicine)
Sjogren syndrome is a debilitating condition in which the patient's immune system destroys all glands producing secretions. We have developed an ELISA assay that can detect the onset of the disease before the symptoms occur, which is presently impossible. This invention is available for licensing in North America and Europe.

Human Immunodeficiency Virus I (HIV I) Treatment Monitoring Assay
Dawn P. Wooley, Ph.D., Courtney Stanforth
One of the biggest challenges in the treatment of HIV infection results from the extreme instability of the genetic material of the virus. These constant changes in genetic composition often result in viral resistance or ineffective drug treatment during disease progression. Our assay enables us to determine the ideal therapeutic course and schedule to improve effectiveness of HIV chemotherapy. This invention is available for licensing worldwide.

A Cutting-Edge Method to Identify Novel Anti-Cancer Agents
John Turchi, Ph.D., Brooke Andrews
This is a straightforward method to process a large number of biological samples in minimal time in order to identify new anti-cancer agents. The advantage of this assay is its simplicity and effectiveness. This technology is available for licensing to the drug discovery industry worldwide.

Forensic Bioinformatics, Inc: Making Sense of DNA Evidence in Criminal Trials
Dan Krane, Ph.D., Carry Rowland, Jason Guilder
Using state-of-the-art DNA analysis, we make DNA testing results meaningful and better organized for criminal trials. In reviewing hundreds of criminal cases in the past year, our bioinformatic approaches have demonstrated aspects of traditionally used testing methods, used to support legal evidence, as being unreliable. Such reliability in evidence testing is critical for the outcome of the criminal trials.


A Novel Method to Accurately Measure the Wall Thickness of Small Tubes
Ping He, Ph.D.
Accurate measurement of the wall thickness of small tubes, such as various catheters used for drug delivery, is an important issue for quality control in tube manufacturing. Our newly patented method uses ultrasound to perform measurement of tube wall thickness with a significantly improved accuracy. This technology has potential applications in manufacture of medical devices and fine instrumentation and is available for licensing worldwide.


Image Guided Surgery Systems
Arthur Goshtasby, Ph.D., Lubamir Vagorchev
We are developing software products that enable surgery to be easier and more precise. These software products could be of interest to surgeons (neurologists, oncologists) and radiologists. We are seeking potential partners in the medical and surgical device industry.

Quantitative Bone Evaluation
Julie Skipper, Ph.D., Thomas Hangartner, Ph.D., Sujata Kamath and David Short

  1. Mass Screening Method for Osteoporosis (patent pending)
    We have developed a state-of-the-art turnkey system for accurate osteoporosis screening.
  2. Analysis of Width and Density of Fine Structures by Computed Tomography (U.S. patents)
    This method significantly increases the measurement accuracy of size and density of the scanning system, which results in improved image quality and interpretation.
  3. Phantom and Method for Quality Assurance and Control of Bone Absorptiometry
    This method consists of a retroactive correction system that enables early detection of possible apparatus malfunctioning. The advantage of this technology is that it increases the consistency of long-term monitoring of osteoporosis patients, while reducing the risk of misdiagnosis.


Water-based Disease Intervention: Commercial Applications of Harmful Algae Research
Wayne Carmichael, Ph.D., Mary Stukenberg
Our activity revolves around developing tests and novel methods to identify harmful algae and toxins in water supplies. Our goal is to increase effectiveness of the mitigation and management of water quality.

Solving Environmental Problems Using State-of-the-Art Instrumental Method
Roger Gilpin, Ph.D., Joseph Solch
We focus on using and developing sophisticated analytical methods to measure and monitor the presence of highly stable environmental and health hazards which are common industrial as well as waste disposal by-products. We offer an integrated approach to detection, monitoring, and remediation of such increasingly abundant pollutants.

Millimeter-Wave Spectroscopy of Gas Samples for Environmental Sensing
Douglas T. Petkie, Ph.D.
Monolithic Microwave Integrated Circuits (MMICs) enable the realization of a general-purpose analytical spectrometer for detection and quantification of gases related to chemical warfare agents, medical diagnostics of exhaled breath, and environmental sensing. The system attributes include nearly absolute specificity, compact size, and the potential for very low cost detection with multiple fields of use.


Design of Undersea Weapons
Ramana Grandhi, Ph.D., Ed Alyanak, Rajesh Kalavalapally, Rahul Khambaswadkar
Lightweight torpedoes and supercavitating torpedoes need to perform optimally under acoustic blast and operational load conditions. This research addresses multidisciplinary optimization of torpedo shapes and structures, and exemplifies the application of our state-of-the-art engineering software packages NASTRAN and ABAQUS.

UltrafIne Grain Forging Stock Saves Energy, Material, and Manufacturing Costs
Raghavan Srinivasan, Ph.D., Bala Cherukuri, Teodora Nedkova
We have a new technology for producing ultrafine grain (UFG) aluminum (grain size < 10 microns) through severe plastic deformation (SPD). Initial use of this method has shown that considerable saving in manufacturing costs can be realized through higher material yield, lower forging temperatures, and shorter heat treatment times. This technology is available for licensing.


The Information Technology Research Institute (ITRI)
Nickolaos Bourbakis, Ph.D., Ming Yang and Jun Lu
The ITRI is a multidisciplinary research and development organization dedicated to leveraging multidisciplinary expertise in order to increase technology adoption and accelerate the transfer of research innovations into the marketplace. The institute combines traditional academic strengths in research and education with the university's role as an economic development partner.

The Advanced Data Management & Analysis (ADMA) Wright Center of Innovation (WCI)
Joseph F. Thomas, Jr., Ph.D.
The new ADMA Wright Center of Innovation will leverage world-class research with robust commercialization of data management solutions to address crucial marketing needs in data mining, security, visualization, and related areas. The center comprises prestigious academic and industrial partners such as The Ohio State University, University of Cincinnati, Lexis-Nexis, Reynolds & Reynolds or NCR, to name only a few. This new Wright Center of Innovation was created from the award by the Ohio Department of Development of an $11 million state grant to drive the creation of high-paying jobs in information technology in Ohio.

Optimization Solutions in Logistics, Transportation, Media, and Services
Xinhui Zhang, Ph.D., Arvind Chakravarthy
We have completed several projects based on optimization programming techniques to address various scheduling, management and problems allocation issues that commonly arise in various industry such as Logistics, Transportation, Service Industry, Manufacturing Plants. Our USPS program on simultaneous use of equipment resulted in about $1.6 million in savings per facility and is implemented in 275 facilities nationwide. Our software program could be used to solve many other similar problems in a broad market.

Dayton Development Coalition
Dinsmore and Shohl i-Zone Taft, Stettinius and HollisterOmeris

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