Wright State University
2004-2005
2004-2006 Graduate Catalog
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WSU Graduate Courses - Microbiology and Immunology/M&I

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M&I 675      PATHOGENIC MECHANISMS (Credits: 5)

(Also listed as BMS 775.) This advanced level course will expand the knowledge of basic microbiology by focusing on human-microbial pathogen interactions. The molecular basis of the pathogenic mechanisms will be emphasized. In addition, the student will gain a better appreciation and understanding of the complexities of interactions between microbes and their human hosts.

PREREQUISITE: BIO 210 OR EQUIVALENT MOLECULAR BIOLOGY COURSE
AND BIO 252 OR EQUIVALENT INTRODUCTORY MICROBIOLOGY
COURSE.

M&I 699      SPECIAL PROBLEMS IN MICROBIOLOGY (Credits: 1 TO 4)

Study of the physiological and biochemical processes unique to microorganisms.

M&I 726      IMMUNOLOGY AND BASIC VIROLOGY (Credits: 5)

(Also listed as BMS 802.) Fundamentals of immunobiology and basic virology. Emphasis on the regulatory and cellular level of host immune responses against microbial pathogens, as well as mechanisms of immunopathology, and on the characteristics and molecular biology of virus pathogens.

PREREQUISITE: BIO 202, BIO 402, CHM 216 OR EQUIVALENT.

M&I 727      PATHOGENIC MICROBIOLOGY (Credits: 5)

(Also listed as BMS 803.) Microorganisms pathogenic for humans and animals using the organ system approach. Emphasis on mechanisms of pathogenesis and host resistance. Includes a project segment devoted to the independent study of the mechanisms of pathogenesis in the host-parasite interactions of the infectious agents used.

PREREQUISITE: BIO 202, 402, CHM 216, M&I 726 OR DEPARTMENT
CONSENT.

M&I 728      DIAGNOSTIC MEDICAL MICROBIOLOGY AND IMMUNOLOGY (Credits: 3)

Identification of etiological agents of disease with emphasis on identification of bacteria, fungi, and viruses using culture and immunological methods.

PREREQUISITE: BIO 202, BIO 402, CHM 216 OR EQUIVALENT.

M&I 731      BASIC VIROLOGY (Credits: 3)

(Also listed as BMS 807.) Introduction to the field of virology with emphasis on animal viruses. Intrinsic properties of viruses and their interaction with cells; multiplication, disease production, genetics, and tumor induction. Projects assigned to each student.

PREREQUISITE: BIO 402, BCH 421, M&I 726 OR CONSENT.

M&I 737      RECOMBINANT DNA METHODS LABORATORY (Credits: 6)

(Also listed as BMS 790 and BIO 737.) Microbial and molecular techniques for producing, cloning, and characterizing recombinant DNA molecules; laboratory exercises in gene manipulation gives an understanding of the principles of genetic engineering. Graded pass/unsatisfactory.

PREREQUISITE: BMB(BCH) 750 AND 752 (COULD BE CONCURRENT
ENROLLMENT); BIO 654 AND BIO 734/BMS 779 OR
INSTRUCTOR PERMISSION.

M&I 745      IMMUNOBIOLOGY (Credits: 5)

(Also listed as BMS 812.) Biology of the immune system in terms of current concepts of antibody formation and function. Acquired, delayed, and immediate hypersensitivity are studied with respect to immunological deficiencies, malignancy, tolerance, graft rejection, infection, and acquired resistance.

PREREQUISITE: M&I 726 & 728, BCH 751 & 752.

M&I 770      INTERCELLULAR COMMUNICATION (Credits: 4)

(Also listed as BMS 805, P&B 776, PHA 740.) Introduces the concepts of intercellular communication through an interdisciplinary presentation of immune neuroendocrine system functions. Emphasizes the similarities between the systems and the multidisciplinary approaches used to study each.

M&I 772      MECHANISMS OF CELL DEATH (Credits: 3)

Signalling and molecular mechanisms of apoptotic cell death and relationship to human disease.

PREREQUISITE: PERMISSION OF INSTRUCTOR.

M&I 777      GENE THERAPY (Credits: 4)

(Also listed as BIO 777.) Study of the molecular basis of gene therapy and the use of viral gene delivery systems for the treatment of human disease. Gene therapy strategies are contrasted with various diseases, including cancer and AIDS.

M&I 800      MICROBIOLOGY SEMINAR (Credits: 1)

Graded pass/unsatisfactory.

M&I 801      SEMINAR: JOURNAL CLUB (Credits: 1 TO 5)

Selected topics in microbiology.

M&I 831      SEMINAR TOPICS IN MOLECULAR VIROLOGY (Credits: 3)

(Also listed as BMS 808.) Structure, infectious process, replication, maturation, release, and genetics at the molecular level of the major groups of animal viruses.

PREREQUISITE: M&I 431/731.

M&I 833      SEMINAR TOPICS IN VIRAL ONCOLOGY (Credits: 3)

(Also listed as BMS 809.) Understanding the processes involved in cell transformation by oncogenic viruses.

PREREQUISITE: M&I 431/731.

M&I 840      SPECIAL TOPICS IN IMMUNOLOGY (Credits: 2 TO 5)

(Also listed as BMS 813.) Students select, present, and analyze information from current literature in immunobiology. Seminar/discussion format.

PREREQUISITE: M&I 745 OR DEPARTMENTAL PERMISSION.

M&I 842      SEMINAR TOPICS IN TRANSPLANTATION IMMUNOLOGY (Credits: 3)

Survey of the fundamentals of transplant immunology. Topics include mechanisms of intra- and interspecies rejection, histocompatibility genes and their products, graft-versus-host diseases, immunologically privileged sites, techniques for immuno-suppression, immune tolerance, and the immunobiology of the maternal/fetal relationship.

PREREQUISITE: M&I 745 OR DEPARTMENTAL PERMISSION.

M&I 843      SEMINAR TOPICS IN TUMOR IMMUNOLOGY (Credits: 3)

The host-tumor relationship is studied intensively. Interrelationships between tumor growth and host immune responses are examined at the molecular and cellular levels.

PREREQUISITE: M&I 745 OR PERMISSION OF DEPARTMENT.

M&I 844      SEMINAR TOPICS IN IMMUNE REGULATION (Credits: 3)

Maintenance of immune homeostasis with emphasis on the contributions of lymphocyte subpopulations. Sequelae of immune imbalance are studied.

PREREQUISITE: M&I 745 OR PERMISSION OF DEPARTMENT.

M&I 846      SEMINAR TOPICS IN INFECTION AND IMMUNITY (Credits: 3)

(Also listed as BMS 818.) Focuses on both beneficial and adverse host responses to microbial and metazoan parasites. Effects of infection on immune function are stressed.

PREREQUISITE: M&I 726 AND 745 OR PERMISSION OF DEPARTMENT.

M&I 851      SEMINAR TOPICS IN REPRODUCTIVE IMMUNOLOGY (Credits: 3)

Immunology as it relates to maternal/fetal interactions. Faculty lectures and student presentations on the fetus as a graft, the passive transfer of immunity to the fetus, pregnancy loss, and infertility. May be taken for letter grade or pass/unsatisfactory.

PREREQUISITE: M&I 726/BMS 802.

M&I 852      SEMINAR TOPICS IN CLINICAL IMMUNOLOGY (Credits: 3)

Immunology as it relates to disease processes. Faculty lectures and student presentations on hypersensitivity diseases, immune deficiency diseases, immunologic diagnosis of disease, tumor immunology, and immunotherapy. May be taken for letter grade or pass/unsatisfactory.

PREREQUISITE: M&I 726/BMS 802.

M&I 899      MICROBIOLOGY RESEARCH (Credits: 2 TO 18)

Supervised thesis research.


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