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Mysteries of the Human Brain
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The Human Brain
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Dr. Oliver Sacks
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The Importance of Neuroscience


Today, one in five North Americans suffer from a debilitating neurological disease. With humans living longer, this statistic is believed to increase to one in every two.

Consciousness. Emotion. Sleep. Creativity. Mental health. Intelligence. Memory. Learning. Imagination. Sight. Hearing. Touch. Smell. Taste. Movement. Balance. Coordination.

All of these characteristics, if the brain functions correctly, are taken for granted. However, when the brain or nervous system work improperly the results can be devastating. Brain Disorders can compromise many of life's normal activities and can include blindness, insomnia, Multiple Sclerosis, Depression, Alzheimer's Disease, deafness, Parkinson's Disease, Schizophrenia, paralysis, dyslexia, Autism, chronic pain, retardation, or attention deficit disorders.

"Advances in neuroscience are happening at such an incredible rate that it's difficult for the public to keep up," said University of Saskatchewan Professor Sergey Fedoroff. Working together worldwide, scientists are striving to realize the vast complexities of the brain and its disorders. Treatments, cures, and, above all, knowledge are the possibilities that continue to be discovered through neuroscientific research.

Wright State University has entered into this field of research through The Center for Brain Research. The Center was established in 2000 with a gift from the Kettering Fund. Robert E.W. Fyffe, Ph.D, was appointed as the Center's director. The Center's mission is to promote interdisciplinary research designed to improve our understanding of neural communication mechanisms in health and disease.

The Center promotes interdisciplinary investigations from the level of gene expression in single neurons to imaging of localized regions of the human brain. The combination of structural and functional studies represent an integrative focus for experimental investigation of neural development; cellular responses to injury, disease, or genetic modification; and the mechanisms that underlie communication between nerve cells and the processing of information through brain and spinal cord circuits. Ongoing studies encompass signal transduction mechanisms; development of synapses and circuits; homeostatic mechanisms; control of neuroendocrine, sensory and motor systems; sensori-motor integration; and brain imaging in mental illness.

The recent development of probes and microscopic techniques for localizing critical molecules in neurons, as well as new noninvasive imaging methods that can directly link brain function to behavior, have provided breakthroughs in the way we view the brain, revealing the diversity and complexity of the constituent neurons and circuits. The fundamental studies undertaken by our researchers hopefully will continue to contribute to the massive efforts of the neuroscience community at large to meet the challenge of describing how the brain works and how the nervous system responds to injury.

For more information, please visit The Neuroscience Institute.

 


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