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Abstracts Kisinovsky I; Mehta A; Ben Turkia H; Kabra M; Lukina EA; Giraldo P; Kishnani PS; Elstein D; Zahrieh D; Hangartner TN; Cohn GM; Crombez E; Zimran A (2013): Bone mineral density in adults with type 1 Gaucher disease receiving velaglucerase alfa 60 U/kg every other week: 2-year results. Congreso Latinoamericano de Enfermedades Lisosomales (COLATEL); 27 February - 1 March 2013; Buenos Aires, Argentina. Kisinovsky I; Kabra M; Lukina EA; Giraldo P; Kishnani PS; Mehta A; Elstein D; Wang N; Hangartner TN; Ben Turkia H; Cohn GM; Crombez E; Zimran A (2013): Bone mineral density response to enzyme replacement therapy over 2 years in adults with type 1 Gaucher disease. Congreso Latinoamericano de Enfermedades Lisosomales (COLATEL); 27 February - 1 March 2013; Buenos Aires, Argentina. Mehta A, Ben Turkia H, Kabra M, Lukina EA, Giraldo P, Kisinovsky I, Bavdekar A, Ben Dridi M-F, Gupta N, Kishnani PS, Elstein D, Zahrieh D, Hangartner TN, Crombez E, Zimran A (2012): Bone mineral density in adults with type 1 Gaucher disease receiving velaglucerase alfa 60 U/kg every other week: 2-year results. 10th European Working Group on Gaucher Disease (EWGGD) Meeting, 28-30 June, 2012; Paris, France. Zimran A, Kabra M, Lukina EA, Giraldo P, Kisinovsky I, Bavdekar A, Ben Dridi M-F, Kishnani PS, Mehta A, Elstein D, Wang N, Hangartner TN, Crombez E, Ben Turkia H (2012): Bone mineral density response to enzyme replacement therapy over 2 years in adults with type 1 Gaucher disease. 10th European Working Group on Gaucher Disease (EWGGD) Meeting, 28-30 June, 2012; Paris, France. Ben Turkia H, Gonzalez DE, Kabra M, Lukina EA, Giraldo P, Kisinovsky I, Bavdekar A, Ben Dridi M-F, Gupta N, Kishnani PS, Mehta A, Elstein D, Wang N, Hangartner TN, Crombez E, Zimran A (2012): Bone mineral density response to enzyme replacement therapy over 2 years in adults with type 1 Gaucher disease. Society for the Study of Inborn Errors of Metabolism (SSIEM) Annual Symposium, 4-7 September 2012; Birmingham, UK. Ben Turkia H, Gonzalez DE, Kabra M, Lukina EA, Giraldo P, Kisinovsky I, Bavdekar A, Ben Dridi M-F, Gupta N, Kishnani PS, Mehta A, Elstein D, Zahrieh D, Hangartner TN, Crombez E, Zimran A (2012): Bone mineral density in adults with type 1 Gaucher disease receiving velaglucerase alfa 60 U/kg every other week: 2-year results. Society for the Study of Inborn Errors of Metabolism (SSIEM) Annual Symposium, 4-7 September 2012; Birmingham, UK. Khan A, Hangartner TN, Weinreb NJ, Taylor JS, Mistry PK (2011): Risk factors for developing fractures or avascular osteonecrosis (AVN) in patients with type 1 Gaucher disease: analysis from the ICGG Gaucher registry. 8th Annual WORLD Synmposium, San Diego, CA, 8-10 February 2012, Khan A, Hangartner TN, Weinreb NJ, Taylor JS, Mistry PK (2011): Risk factors for developing fractures or avascular osteonecrosis (AVN) in patients with type 1 Gaucher disease: analysis from the ICGG Gaucher registry. ASHG/ICHG 2011 Meeting, Montreal, Canada, 11-15 October 2011, Abstract 1318T. Jayakar R, Cabal A, Szumiloski J, Sardesai S, Phillips E, Winkelmann C, McCracken P, Hangartner T, Williams D (2011): Evaluation of HR-pQCT in non-human primates for monitoring the effect of odanacatib on bone microarchitecture. J Bone Miner Res 26 (Suppl 1): SU0066. Purcell ML, Somayajula S, Brown K, Jayakar RY, Szumiloski J, Cook JJ, Hangartner TN, Dardzinski B, Evolhoch J, Williams DS (2011): Customized quantitative computed tomography longitudinal analysis to determine treatment effect of odanacatib and alendronate in rhesus. 2011 World Molecular Imaging Congress, 10 September 2011, San Diego, California, Abstract P814. Williams DS, McCracken PJ, Jayakar RY, Purcell M, Mathers P, Svitz A, Szumiloski J, Cabal A, Dardzinski BJ, Motzel SL, Hangartner TN, Hargreaves RJ, Evelhoch JL, Duong LT, Cook JJ (2011): Head-to-head comparison of treatment effects of odanacatib to alendronate in the ovariectomized rhesus monkey: a longitudinal multi-modality imaging study. 3rd Joint Meeting of the European Calcified Tissue Society and the International Bone and Mineral Society, 7-11 May 2011, Athens, Greece. Hangartner TN, Short DF, Zemel BS, Gilsanz V, Kalkwarf HJ, Lappe JM, Mahboubi S, Oberfield SE, Shepherd JA, Winer KK (2010): Modeling of pediatric spine BMD with consideration of anthropometric parameters. Osteoporos Int 21 (Suppl. 5): S682 Hangartner T, Weinreb N, Kaplan P, Cole A, Gwosdow A, Mistry P (2010): Osteopenia in Gaucher disease develops early in life: response to imiglucerase enzyme therapy in children, adolescents and adults. ASBMR 2010 Annual Meeting, Toronto, Canada, 15-19 October 2010, Abstract SA0444. McCracken P, Jayakar R, Purcell M, Mathers P, Savitz A, Szumiloski J, Cook J, Dardzinski B, Hangartner T, Motzel S, Hargreaves R, Evelhoch J, Duong L, Williams D(2010): A multi-modality imaging comparison of odanacatib to alendronate in the ovariectomized rhesus monkey. ASBMR 2010 Annual Meeting, Toronto, Canada, 15-19 October 2010, Abstract SA0435. Gilsanz V, Chalfant J, Kalkwarf H, Zemel B, Lappe J, Oberfield S, Shepherd J, Hangartner T, Frederick M, Huang X, Mahboubi S, Sesmangles J, Wren T, Winer K (2010): Age at onset of puberty predicts bone mass in young adulthood. ASBMR 2010 Annual Meeting, Toronto, Canada, 15-19 October 2010, Abstract 1179. Mistry PK, Weinreb NJ, Kaplan P, Cole JA, Gwosdow AR, Hangartner TN (2010): Osteopenia in Gaucher disease develops early in life: response to imiglucerase enzyme therapy in children, adolescents and adults. American Academy of Pediatrics National Conference, San Francisco, 2-5 October 2010. Mistry PK, Weinreb NJ, Kaplan P, Cole JA, Gwosdow AR, Hangartner TN (2010): Osteopenia in Gaucher disease develops early in life: response to imiglucerase enzyme therapy in children, adolescents and adults. SSIEM Annual Symposium, Istanbul, 31 August - 3 September 2010. Khan A, Hangartner TN, Weinreb NJ, Cole JA, Taylor JS, Gwosdow AR, Mistry PK (2009): Characterizing extra-skeletal phenotype and biomarkers of type-1 Gaucher disease patients with avascular necrosis (AVN) or fractures: a study from the ICGG Gaucher Registry. Molecular Genetics and Metabolism 98:81. Hangartner TN, Short DF, Zemel BS, Gilsanz V, Kalkwarf HJ, Lappe JM, Oberfield S, Shepherd JA, Winer K (2009): Fitting of BMD with consideration of confounding parameters. Bone 45 (Suppl. 2): S87. Grabowski GA, Hangartner T, Kaplan P, Maas M, Mariani G, McHugh K, Moore S, Vellodi A, Yee J, Steinbach L (2008): Guidelines for the assessment and monitoring of bone disease in children with Gaucher disease. Lysosomal Disease Network World Symposium 2008, Las Vegas, NV, 13-15 February 2008. Alladi S, Abhange SK, Hangartner TN (2008): Peripheral computed-tomography scanner for high-resolution in-vivo imaging of trabecular-bone microarchitecture. Proceedings of The 18th International Bone Densitometry Workshop, Pugnochiuso, Italy, 15-19 June 2008: 30. Hangartner TN, Short DF (2008): Fitting of BMD with consideration of confounding parameters. Proceedings of The 18th International Bone Densitometry Workshop, Pugnochiuso, Italy, 15-19 June 2008: 61. McCracken PJ, Jayakar RY, Duong LT, Hangartner TN, Williams DS (2008): Efficacy of odanacatib in the ovariectomized rhesus monkey as measured with pQCT. JBMR 23 (Suppl. 1): S459. Hangartner TN (2008): Diagnosis of osteoporosis in China: a cost-effective approach. Proceedings of The 6th International Conference on Bone and Mineral Research & The 8th International Osteoporosis Symposium, Hohhot, China, 19-22 September 2008:18. Hangartner TN, Varghese BA, Miller ME (2008): Bone-strength analysis from plain radiographs of the forearm. Proceedings of The 6th International Conference on Bone and Mineral Research & The 8th International Osteoporosis Symposium, Hohhot, China, 19-22 September 2008:18:24. Wenstrup R, Kacena K, Kaplan P, Pastores G, Prakash-Cheng A, Zimran A and Hangartner T (2007): The effect of enzyme replacement therapy with imiglucerase on bone mineral density in type 1 Gaucher disease. Presented at the 4th Annual LSD Symposium, Vienna, Austria, 29-31 March 2007. Schousboe JT, Wilson KE, Hangartner TN (2007): Accurate detection of abdominal aortic calcification on VFA images. 7th International Symposium on Osteoporosis: Translating Research into clinical Practice, Washington, DC, 18-22 April 2007. Schousboe JT, Wilson KE, Hangartner TN (2007): Accurate detection of abdominal aortic calcification on lateral spine DXA (VFA) images. Calcif Tissue Int 80 (Suppl. 1): S147. Carlino W Hangartner TN, Blades, HZ, Vickers Y, Bishop NJ (2007): Bone mass and architecture with and without fractures. Bone 40 (Suppl. 1): S32-33. Hangartner TN, Varghese BA, Miller ME (2007): Assessment of bone strength through finite element analysis based on radiographs of the forearm. Bone 40 (Suppl. 1): S48. Schousboe JT, Wilson KE, Hangartner TN (2007): Accurate detection of abdominal aortic calcification on lateral spine DXA (VFA) images. Bone 40 (Suppl 2): S182. Hangartner TN (2007): Assumptions and limitations in image-based strength assessment of bone. JBMR 22 (Suppl. 1): S226. McCracken PJ, Jayakar RY, Duong LT, Hargreaves R, Hangartner TN, Williams DS (2007): Model effects in the ovariectomized rhesus monkey as measured with pQCT. JBMR 22 (Suppl. 1): S302. McHugh K, Grabowski GA, Hangartner T, Kaplan P, Maas M, Mariani G, Moore S, Vellodi A, Yee J, Steinbach L (2007): Guidelines for the assessment and monitoring of bone disease in children with Gaucher disease. Society for the Study of Inborn Errors of Metabolism 2007 Annual Meeting, Hamburg, Germany, 4-7 September 2007. Maas M, Grabowski G, Hangartner T, Kaplan P, Mariani G, McHugh K, Moore S, Vellodi A, Yee J, Steinbach L (2007): Guidelines for assessing and monitoring bone disease in children with Gaucher disease. European Study Group for Lysosomal Storage Disorders, Perugia, Italy, 27-30 September 2007. Mariani G, Grabowski G, Hangartner T, Kaplan P, Maas M, McHugh K, Moore S, Vellodi A, Yee J, Steinbach L (2007): Guidelines for the assessment and monitoring of bone disease in children with Gaucher disease. Radiological Society of North America, Chicago, IL, 25-30 November 2007. Hangartner TN (2006): Impact of long-term precision on least significant change. J Clinical Densitometry 9: 238. Hangartner TN, Varghese B and Miller ME (2006): Analysis of pediatric radiographs of forearms - morphologic differences that separate children suffering from fractures due to unintentional injury or intentional injury. Proceedings of The Fourth Clare Valley Bone Meeting, Clare Valley, South Australia: O16. Wenstrup R, Kacena K, Kaplan P, Pastores G, Prakash-Cheng A, Zimran A and Hangartner T (2006): The effect of enzyme replacement therapy with imiglucerase on bone mineral density in type 1 Gaucher disease. Proceedings of the European Working Group on Gaucher Disease 2006. Wenstrup R, Kacena K, Kaplan P, Pastores G, Prakash-Cheng A, Zimran A and Hangartner T (2006): Bone mineral density in type I Gaucher disease: prevalence of fractures and effect of treatment with imiglucerase. J Inherit Metab Dis 29: Suppl 1:64 Hangartner TN, Varghese B and Miller ME (2006): Analysis of pediatric radiographs of forearms: morphologic differences that separate children suffering from fractures due to unintentional injury or intentional injury. Proceedings of World Congress on Medical Physics and Biomedical Engineering 2006, Soul, Korea, 4820. Wenstrup R, Kacena K, Kaplan P, Pastores G, Prakash-Cheng A, Zimran A and Hangartner T (2006): The effect of enzyme replacement therapy with imiglucerase on bone mineral density in type 1 Gaucher disease. Presented at the annual meeting of The American Society of Human Genetics, New Orleans, LA. Available from http://www.ashg.org/genetics/ashg06s/. DiMeglio LA, Short D and Hangartner TN (2006): pQCT precision: the importance of accurate repositioning. JBMR 21 (Suppl. 1): S222. Hangartner TN (2006): Image-based strength assessment of bone. Proceedings of The 17th International Bone densitometry Workshop, Kyoto, Japan: 38. Wenstrup R, Kacena K, Kaplan P, Pastores G, Prakash-Cheng A, Zimran, A, Hangartner T (2005): Effect of enzyme replacement therapy on bone mineral density in type I Gaucher disease. Blood 106 (11): Abstract 3895. Hangartner TN (2005): Short- and long-term precision of Lunar Prodigy and Hologic Delphi scanners. JBMR 20 (Suppl. 1): S328. Hangartner TN, Goradia D, Short DF (2005): Repositioning of the region of interest in the radius of the growing child in follow-up measurements by pQCT. Proceedings of the 2005 International Symposium on Quality of Bone and Scaffold Biomaterials, Hong Kong: 207. Hangartner TN, Ward KA (2005): Thresholding technique for accurate analysis of density and geometry in QCT, pQCT and μCT. Proceedings of The 2nd International Conference on Osteoporosis and Bone Research, Chengdu, China: 11 & 267-272. Hangartner TN (2005): Comparison of short- and long-term precision of Lunar Prodigy and Hologic Delphi scanners. J Clinical Densitometry 8: 238. Ward KA, Harrison EH, Hangartner TN, Adams JE (2004): The effects of threshold selection upon measurement of bone density and geometry by peripheral quantitative computed tomography. Osteoporosis Int 15 (Suppl 2): S26-S27. Landoll JD, Mobley SL, Ha E, Badenshop-Stevens NE, Hangartner TN, Matkovic V (2004): Children with bone fragility fractures have reduced volumetric bone mineral density of the radius. J Bone and Mineral Res 19: S87. Villata RB, Hangartner TN (2004): Physical activity and bone density: countermeasure strategies for low Gz environments. Aviat Space Environ Med 75:S437. Hangartner T (2004): Quality assurance and control in DXA: Are the traditional phantoms adequate? Proceedings of the 16th International Bone Densitometry Workshop, Annecy, France: 168. Ward K, Hangartner T, Harrison E, Adams J (2004): A comparison of manufacturer and user-defined thresholds for analysis of bone geometry and density by peripheral quantitative computed tomography (pQCT). Proceedings of the 16th International Bone Densitometry Workshop, Annecy, France: 153. Harrison E, Ward K, Hangartner T, Adams J (2004): Estimating the effect of positioning on the measure of BMD by pQCT at the distal radius. Proceedings of the 16th International Bone Densitometry Workshop, Annecy, France: 47. Hangartner TN, Skipper JA (2003): A new screening method for osteoporosis: radiographic absorptiometry of the mandible. Proceedings of the 2003 International Symposium on Osteoporosis and Geriatrics, Zhangjiajie, China:13-14 Hangartner TN, Shah D (2003): Modeling of blurring due to finite slice width in computed tomography. Proceedings of the WC2003 World Congress of Medical Physics and Biomedical Engineering, Sydney, Australia: 1652. Kausthubh NA, Hangartner TN, Ezzeddine BM (2003): Phantom to evaluate imaging of atherosclerotic coronary arteries in motion by spiral computed tomography. 4th International Conference on Cardiac Spiral CT, Cambridge, MA. Delmas PD, Hangartner TN, Li Z, Cooper C (2002): Relationship between spine bone mineral density and vertebral fracture risk for antiresorptive agents using individual patient data vs. summary statistics. Osteoporos Int 13 (Suppl 3): S12. Hangartner TN, Short DF (2002): Overcoming the partial-volume effect in cortical analysis using computed tomography. Proceedings of the 2002 International Osteoporosis Conference, Shanghai, China: 134-135. Miller ME, Short DF, Hangartner TN (2002): Cortical and trabecular bone density values in normal children measured by pQCT. Calcif Tissue Int 70: 374. Hangartner TN, Miller ME (2001): Computed-tomography bone-density measurements in normal pre- and post-pubertal females. Bone 28: S197. Miller ME, Hangartner TN (2001): Computed tomography (CT) bone density measurements in normal prepubertal and postpubertal females. Ped Res 49:159A. Hangartner TN, Short DF (2001): Quantification by computed tomography of width and density of narrow bone structures suffering from partial volume effect. Med Phys 28: 1818. Buckland-Wright C, Bird C, Tonkin C, Hangartner T, Ritter-Hrncirik C, Cline G, Meyer J (2001): X-ray technologist's reproducibility in radiography of osteoarthritic (OA) knees for a multicentre, multinational clinical trial. Arthritis Rheum 44: S385. Eastell R, Reid D, Watts N, Roux C, Genant H, Adami S, Hangartner T, Miller P, Sorensen O, Hooper M, Ethgen D, Valent D (2000): Risedronate induces rapid and sustained reductions in vertebral fracture risk in postmenopausal women with established osteoporosis. Osteoporos Int 11, (Suppl 1): S26. Miller ME, Hangartner TN (2000): Successful treatment of severe osteogenesis imperfecta with oral alendronate. Am J Hum Genet 67 (Suppl 2): 431. Hangartner TN, Short DF (2000): Influence of scanning and reconstruction parameters on the measured density of fine structures in computed tomography. Osteoporos Int 11 (Suppl 3): S43 Skipper J, Hangartner T (2000): Improvement of energy resolution of NaI-photomultiplier detector using spectral deconvolution. 2000 World Congress of Medical Physics and Biomedical Engineering, 23-28 July 2000, Chicago, IL, FR-B307-04 Hangartner T, Short D (2000): Quantitative evaluation of width and density of fine structures by computed tomography. 2000 World Congress of Medical Physics and Biomedical Engineering, 23 - 28 July 2000, Chicago, IL, TH-E307-06 Zaim A, Hangartner T (2000): Prediction of mechanical strength of bone using finite element analysis and computed tomography. 2000 World Congress of Medical Physics and Biomedical Engineering, 23 - 28 July 2000, Chicago, IL, WE - B328-03. Miller ME, Hangartner TN (2000): Successful treatment of severe osteogenesis imperfecta with oral alendronate. Ped Res 47:242A. Binkley TL, Speckler BL, Hangartner TN (1999): Bone parameters in preschool children as measured by peripheral quantitative computed tomography. Validation and technique. J Bone and Mineral Res 14: S251 Watts N, Roux C, Genant H, Adami S, Hangartner T, Miller P, Sorenson O, Hooper M, Ethgen D, Valent D (1999): Risedronate reduces vertebral fracture risk after the first year of treatment in postmenopausal women with established osteoporosis. J Bone and Mineral Res 1: S136 Miller, M, Hangartner, TN (1999): Temporary brittle bone disease (TBBD): Association with decreased fetal movement and osteopenia. First International Conference on Children's Bone Health. 4-7 May, 1999 MECC Maastricht: 68. Watts N., Hangartner T., Chesnut C., Genant H., Miller P., Eriksen E., Chimes A., Axelrod D., McKeever C (1999): Risedronate treatment prevents vertebral and non-vertebral fractures in women with postmenopausal osteoporosis. Calcif Tissue Int 64 (Suppl. 1): S42 Hangartner TN (1999): Bone densitometry: quality assurance and control. Osteoporosis Update 1999: P81 Hangartner TN (1998): How do u convince yourself that a bone scanner is working right? Bone 23 (Suppl.): SA307 Miller ME, Hangartner TN (1997): CT bone density in a case of osteogenesis imperfecta - type I (OI) presenting with suspected child abuse. Ped Res 43: 116A Miller ME, Hangartner TN (1997): CT bone density measurements in infants with temporary brittle bone disease associated with decreased fetal movement/intrauterine confinement and controls. Ped Res 41: 96A Hangartner TN (1997): Technical problems in longitudinal measurements with dual-energy absorptiometry. Osteoporosis Int 7: 257 Hangartner TN, Gilsanz V (1996): The measurement of the material density of bone by computed tomography. Current Research in Osteoporosis and Bone Mineral Measurement IV: 1996: 89 Miller ME, Hangartner TN (1996): Increased cortical bone density in adults with osteogenesis imperfecta type 1 compared to their affected children. Ped Res, 39: 147A Miller ME, Hangartner TN (1996): The association between temporary brittle bone diseases and intrauterine confinement. Ped Re, 39: 83A Hangartner TN, Miller ME (1996): Bone density in children with osteogenesis imperfecta and multiple unexplained fractures. Osteoporosis Int 6: 86 Miller ME, Hangartner TN (1995): Computed tomography (CT) bone density measurements in a family with osteogenesis imperfecta (OI) - type I. Am J Hum Genet 57: A306 Hangartner TN, Gilsanz V (1995): Evaluation of width and density of cortical bone by computed tomography. J Bone Miner Res 10, Suppl. 1: S472 Miller ME, Hangartner TN (1995): Computed tomography (CT) bone density in children with osteogenesis imperfecta (OI), infants with multiple unexplained fractures (MUF), and controls. Ped Res, 37: 150A Hangartner TN, Rodgers MM, Glaser RM (1994): Functional electrical stimulation reduces bone density loss in patients with spinal cord injury. Phys. Med. Biol 39a: 866 Hangartner TN, Gilsanz V (1994): The accurate measurement of cortical bone by computed tomography. Phys. Med. Biol 39a: 313 Hangartner TN, Rodgers MM, Glaser RM (1994): Reduction of bone density loss in patients with spinal cord injury using functional stimulation. Bone and Mineral 25 (Sup. 2): S38. Hangartner TN, Gilsanz V (1994): Constant cortical density is a requirement for the accurate measurement of cortical thickness by CT. Bone and Mineral 25 (Sup. 2): S4. Moradmand K, Hangartner TN, Goldfinger MD (1993): Poisson-process electrical stimulation: circuit and axonal responses. Society for Neuroscience Abstracts 19: 1748. Loro ML, Hangartner TN, Chuang KS, Ferreira M, Goodman W, Boechat MI, Gilsanz V (1993): Osteodystrophy in alcoholic liver disease. Calcif Tissue Int 52: 160. Trulzsch D, Grandhi N, Hangartner TN (1992): Die hepatische Osteodystrophie bei alkolischer Leberzirrhose. Klinische Wochenschrift 69, Suppl. XXIII: 126. Grandhi N, Hangartner TN, Trulzsch TV (1992): Hepatic osteodystrophy in alcoholic liver disease. Research Competition for Associates Abstracts, 73rd Annual Session of the American College of Physicians, San Diego, CA: 42. Hangartner TN, Rodgers MM, Glaser RM (1991): Bone-density in spinal-cord injury patients. Osteoporosis International 1: 210. Hangartner TN, Rodgers MM, Glaser RM (1990): Regional bone-density analysis in the tibia of patients with spinal cord injury. Radiology 177(P): 316.

Updated January, 2013