Current Projects

Completed Projects


  • L-thyroxine impact on bone mineral density in primary hypothyroidism 

  • Bone density changes in spinal-cord injured patients

  • Bone density changes in stroke patients

  • A phase III study of intermittent cyclical Tiludronate in the treatment of established post-menopausal osteoporosis 

  • A randomized, double-blind, placebo-controlled, multi-center, parallel group study to determine the efficacy and safety of risedronate (NE-58095) in the treatment of post menopausal women with established osteoporosis-related vertebral deformities

  • A four-year (three-year core and one-year partial crossover), double-blind, multi-center, placebo-controlled study of the effects of three different doses of Calcimar (synthetic salmon calcitonin, injectable) on bone mineral density, stature, and biochemical markers of bone turnover in women with established postmenopausal osteoporosis.

  • Change of bone density during pregnancy and lactation 

  • The use of computed tomography for measurement of bone density to distinguish fractures of osteogenesis imperfecta from child abuse

  • A randomized, comparative multi-center clinical trial evaluating Norian SRS and conventional treatment in unstable metaphyseal fractures of the distal radius 

  • Disuse osteoporosis : changes in biochemical parameters during and following simulated micro-gravity

  • Measurement of bone density changes in simulated micro-gravity using an enhanced gamma computed tomography device

  • Qualification of radiologic technologists in North America for the test-retest reliability of measurements of the tibiofemoral joint space width in subjects with osteoarthritis of the knee  

  • Radiographic knee procedures for clinical study in knee osteoarthritis 

  • A randomized, double blind, parallel, multi-center, placebo-controlled, two year study to determine the efficacy and safety of orally administered 5 and 15 mg/day, and 50 mg/week risedronate in patients with medial compartment knee osteoarthritis in North America 

  • A randomized, double-blind, multicenter study to evaluate the tolerability and effectiveness of etoricoxib 90 mg q.d. versus diclofenac sodium 75 mg b.i.d. in patients with rheumatoid arthritis

  • A randomized, double-blind, placebo-controlled, multicenter, parallel-group study of one-year duration followed by 2 years of open-label treatment to determine the safety and efficacy of orally administered 2.5 mg or 5.0 mg risedronate in children > 4 to < 16 years old with osteogenesis imperfecta




Updated January, 2013