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Applied and Predictive Toxicology

The dose makes the poison.
Toxicology is part of the solution.


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Each and every day we breathe, ingest, apply, and dispose of chemicals. The effects of these chemicals on our health and well being and on our environment range from miraculous to disastrous. As our technology driven culture continues to develop new chemicals for agricultural, medicinal, military, and industrial uses, we need to understand what the ecological, societal, and health risks/effects of these chemicals will be.

If these kinds of problems/issues interest you, then you should consider training in the area of Applied and Predictive Toxicology. You will find many opportunities to expand your knowledge and contribute to the advancement of this field among the faculty from the three departments (Biology, Biochemistry and Molecular Biology, and Pharmacology and Toxicology) who are actively engaged in research addressing toxicological problems. The inherently interdisciplinary nature of this area utilizes the latest molecular biological, chemical detection, and immunocytochemical techniques and applies them to a broad range of problems of immediate and long-term relevance.

Areas of faculty expertise include:

 

small gold bullet Aquatic toxicology
small gold bullet Dermal toxicology
small gold bullet Ecotoxicology
small gold bullet Environmental toxicology
small gold bullet Immunotoxicology
small gold bullet Risk assessment
small gold bullet Toxicogenomics
small gold bullet Stress/toxicant interactions

 


State of the art approaches currently employed include:

 

small gold bullet DNA and protein chip array analysis
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Laser scanning confocal microscopy
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In vitro and in vivo monitoring of toxicant effects
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HPLC and LC/MS-based detection and quantification of chemicals

 

Participating faculty and areas of research
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Department of Pharmacology and Toxicology
  • David Cool, Ph.D. Molecular mechanisms of intracellular sorting of prohormones. [home][e-mail]
  • John Frazier, Ph.D. In vitro toxicology, biologically-based modeling, hepatocyte culture [home][e-mail]
  • Robert Grubbs, Ph.D. Signal transduction/growth factors/muscarinic receptors. [home][e-mail]
  • Thomas Lockwood, Ph.D. Toxicology; environmental interactions. [home][e-mail]
  • Jim Lucot, Ph.D. Neurochemical/behavioral response to toxins. [home][e-mail]
  • James N. McDougal, Ph.D. Skin irritation. Biologically-based pharmacokinetic modeling of chemical interactions of the skin [home][e-mail]
  • Mariana Morris, Ph.D. (Department Chair) Neuroendocrinology/cardiovascular function. [home][e-mail]
  • Courtney Sulentic, Ph.D. Cellular and molecular immunotoxicology. [][e-mail]
Department of Biological Sciences
  • Wayne Carmichael, Ph.D. Aquatic toxicology; blue-green algae [bio] [home][e-mail]
  • Keith Grasman, Ph.D. Ecotoxicology, immunotoxicology, endocrine disrupters [home][e-mail]
Department of Biochemistry and Molecular Biology
  • Nicholas V. Reo, Ph.D. Nuclear magnetic resonance (NMR) studies of liver metabolism; hepatotoxicity and effects of peroxisome proliferators. Dissertation qualified. [home][e-mail]
Department of Computer Science and Engineering
  • Mateen Rizki, Ph.D. Pattern recognition, machine learning (self-computing), ATR, image processing [home][e-mail]

 

  Areas of concentration: Applied Biomedical Computation | Applied and Predictive Toxicology | Cell Biology & Physiology | Chemical and Structural Biomedical Sciences | Epidemiology | Immunology | Medical Physics and Engineering | Molecular Biology and Biochemistry | Neuroscience

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Complete your application by March 1
Contact Diane Ponder in the BMS PhD Program Office
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last modified on September 17, 2003
Comments, questions and suggestions are welcome. (sjm)
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