Chemistry
plays a pivotal role in the biomedical sciences especially
as the functional properties of biologically relevant
molecules are encoded in their covalent and non-covalent
structures. To understand such structure/function
relationships relevant to metabolic processes and
protein/enzyme function, as well as the molecular
basis of drug action, scientists in this multidisciplinary
area of concentration routinely employ cutting-edge
techniques spanning the entire breadth of the chemical/biological
interface. The complementary sub-specialties of this
area include: computational methods for molecular
modeling and design as well as establishing quantitative
structure-activity relationships (QSAR); transient
and steady state spectroscopic methods relevant to
macro molecules; biological magnetic resonance; novel
technologies for the rapid-synthesis, chromatographic
purification and spectroscopic analysis of organic
molecules of pharmaceutical interest and biological
macromolecules; a molecular understanding of diverse
metabolic processes.
In the
Chemical and Structural
Biomedical Sciences concentration,
you will have the opportunity to contribute
to advancing our understanding of diverse projects
involving:
Molecular Modeling and Design
Development of Novel Polymeric Supports and Immobilized
Reagents
Combinatorial Chemistry / Solid-Phase Organic
Synthesis
High Throughput Purification and Analysis
Analytical Methods for Drugs and Biological Macromolecules
Quantitative Structure Activity Relationships
Cheminformatics
Protein and enzyme structure and dynamics
Structural basis of catalysis
Metabolic regulation
Participating
faculty and areas of research
Note:
Linked pages will be opened in new windows
- Eric
Fossum, Ph.D. Dendrimers (highly branched polymers).
[home][e-mail]
- Roger
Gilpin, Ph.D. Protein-based chromatography; mass
spectrometry. Dissertation qualified. [e-mail]
- Daniel
Ketcha, Ph.D. Combinatorial chemistry. Dissertation
qualified. [home][e-mail]
- Paul
Seybold, Ph.D. Biophysical chemistry. [home][e-mail]
- Kenneth
Turnbull, Ph.D. Potentially hypotensive mesoionic
compounds; non-linear optical materials. [home][e-mail]
- Gerald
Alter, Ph.D. Enzyme function and dynamics in crowded
solutions. Disertation qualified. [home][e-mail]
- Lawrence
Prochaska, Ph.D. Mitochondrial energy conservation.
Dissertation qualified. [bio]
[home]
[e-mail]
- Nicholas
Reo, Ph.D. Nuclear magnetic resonance (NMR) studies
of liver metabolism; hepatotoxicity and effects
of peroxisome proliferators. Dissertation Qualified.
[home]
[e-mail]
- John
Turchi, Ph.D. Mechanisms of mammalian DNA replication
and repair. Dissertation qualified. [home][research][e-mail]
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